Validation


There were two stages in the development of the SAQ.


  • In the first stage patients with severe asthma were interviewed and domains of quality of life deficit identified1.
  • In the second stage, information from these interviews was used to construct a questionnaire and then patients in focus groups evaluated the questionnaire and suggested changes to wording2. Because of this additional qualitative stage, the SAQ is optimised to the content and wording of severe asthma patients.

Initial quantitative validation has been completed and large scale studies are in train. The validation research programme will include comparison with other HRQoL scales, test-retest reliability, sensitivity to change, and minimally clinically significant difference. Domain scoring will be published later.


  1. Hyland ME, Whalley B, Jones RC, Masoli M. A qualitative study of the impact of severe asthma and its treatment showing that treatment burden is neglected in existing asthma assessment scales. Quality of Life Research. 2015;24:631-9.
  2. Paper submitted, currently under review.